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However, in view of the excellent safety profile of B12, even at high doses, supplementation, ideally as part of a more comprehensive nutritional programme, may still be of value when the clinical picture and/or other factors (e.g

But in general, these folks are more likely to be B12 deficient: vegetarians or vegans people taking certain medications (like metformin, Prilosec, or Pepcid) pregnant and breastfeeding people people over 50 people with atrophic gastritis, celiac disease, Crohns disease, or who have had stomach or intestinal surgery Which form of vitamin B12 is best

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An example of this is pernicious anaemia, a disorder that prevents the body from being able to absorb enough vitamin B12, leading to a lack of red blood cells

[6] [7] It's worth noting that the body can store vitamin B12 in the liver for several years, which provides some protection against short-term dietary inadequacy