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In wound healing, hydrogels made from HA have shown significant potential in supporting tissue repair by adjusting the inflammatory response, improving angiogenesis, and aiding ECM remodeling [9]

Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing CriglerNajjar and Gilbert syndromes: correlation of genotype to phenotype

Vitamin C helps "spare" glutathione by taking on some of the antioxidant workload, and glutathione, in turn, helps recycle Vitamin C after it has neutralized a free radical

& Jain, A

However, in the presence of copper deficiency or ATP7A dysfunction, this regulatory mechanism falters, leading to NMDAR overactivation, calcium overload, and neuronal apoptosis (217, 218)

The occurrence, progression and metastasis of brain tumors such as glioblastoma may be related to ferroptosis, and manipulation of iron death may provide a new strategy for the treatment of brain tumors (Figure 3)