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Phase 2b primary endpoints failed in the largest published trial

Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation

Final Words Vitamin B12 is a powerful nutrient with incredible benefits in the body

A low serum B12 level is the main clue, but it doesn't tell you why it's low

Use a refrigerator thermometer to verify your storage temperature

Many people are unaware they may be deficient, and this deficiency can worsen or even cause chronic pain