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In the case of TGF-1, decreased GCLC mRNA together with cleavage of GCLC protein resulted in decreased GCL activity

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(2025) 122:e241963212

Stem Cells 28 , 734742 (2010)

At the onset of atherosclerosis, compromised vascular endothelium secretes chemokines to recruit circulating monocytes, which then differentiate into macrophages 11

These findings indicate NAC may support oxidative stress reduction in ME/CFS, but robust clinical trials are lacking