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In the first of several votes, the panel of Food and Drug Administration experts on Thursday narrowly voted 8-6 in favor of broadening access to a chemical called BPC-157, one of the most popular peptides among longevity and wellness influencers

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76 , e12948 (2024)

Preclinical animal studies further validate its neuroprotective potential: phillyrin A improves learning and memory in senescence-accelerated mice, activates the Nrf2 signaling pathway in APP/PS1 mice, upregulates antioxidant proteins (NQO1, GPX4), and normalizes cerebral iron content through modulation of TFRC, DMT1, FTH, and FTL gene expression (234)

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require documentation of indication, dosing, and clinical response Biologics (IL-12/23 inhibitor): Ustekinumab (Stelara, J3357) FDA-approved for moderate-to-severe CD