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In addition, engineered bacteria are a promising carrier for drug delivery, and today substantial studies are using engineered bacteria for targeted delivery of interfering RNA (Jiang et al., 2007), DNA vaccines (Kong et al., 2012), proteins (Xie et al., 2017) for the treatment of malignant tumors

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5.1 Intervention strategies 5.1.1 Targeting iron homeostasis Iron chelators such as deferoxamine, deferiprone, and deferasirox bind free ferrous iron (Fe2+), reducing substrate availability for the Fenton reaction and thereby curtailing the lipid peroxidation cascade (152)

TangHYHoHYWuPRChenSHKuypersFAChengMLet alInability to maintain GSH pool in G6PD-deficient red cells causes futile AMPK activation and irreversible metabolic disturbance

(NAC can be bought as a dietary supplement in the United States.) If the patient presents less than eight hours after paracetamol overdose, then acetylcysteine significantly reduces the risk of serious hepatotoxicity