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Detailed understanding of the inhibitory action exerted by targeted RTK inhibitors including those affecting the HGF/c-Met signaling is critical for the durable antitumor responses

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Continue increasing by 0.25 to 0.5 mg every 4 weeks until reaching the target dose or maximum tolerated dose

doi: 10.3389/fphys.2014.00522 76 DemetriusL

FGF21 is an endocrine signal of protein restriction

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