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The upregulation of HO-1 increases the LC3-II/I ratio, decreases mTOR expression, and leads to excessive autophagy, exacerbating ferroptosis in PM2.5-exposed hippocampal neurons

doi: 10.1016/S0378-1119(99)00114-6 39 ChuangYMDuttaNKHungCFWuTCRubinHKarakousisPC

For the AD model, we used a previously described animal model of focal DTR (diphtheria receptor)-expressing astrocytes in APP/PS1 mice (fGiD)

Samples were reconstituted in 90 l of 50% acetonitrile (Fisher Scientific, A955) and transferred to glass vials for LCMS analysis

When the body has the health and the nourishment it needs, it works tirelessly to eliminate acidic toxins and to protect itself

4018-A CLINICAL CHARACTERISTICS AND RISK FACTORS OF EXTRAHEPATIC RECURRENCE AFTER HEPATECTOMY OF HEPATOCELLULAR CARCINOMA WITHOUT INTRAHEPATIC HEPATOCELLULAR CARCINOMA: A MULTI-INSTITUTIONAL 15-YEAR OBSERVATIONAL STUDY Jae Hyun Yoon 1 , Ga Ram You 2 , Sung Bum Cho 2 and Sung Kyu Choi 1 , (1)Chonnam National University Hospital, (2)Hwasun Chonnam National University Hospital Background: Extrahepatic recurrence (EHR) is a well-known poor prognostic factor regarding hepatocellular carcinoma (HCC)