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6.3 Advancing precision medicine The heterogeneity of PD underscores the need for personalized therapy

In addition, the anti-RA mechanism of ginsenoside Rg1 may be related to its anti-inflammatory effect by up-regulating peroxisome proliferators activated receptor- (PPAR-) and then inhibiting the NF-B signaling pathway (131)

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AJNR Am J Neuroradiol

Moreover, an inactivating mutation in the cetacean gene encoding Pol, a polymerase with low fidelity in repairing oxidative DNA damage, suggests that reliance on a higher fidelity polymerase (Pol) may confer tolerance to oxidative damage (Pryor et al., 2015

Hinson JA, Monks TJ, Hong M, Highet RJ, Pohl LR