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B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO prevent stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial

DNA Repair When DNA is exposed to ROS, it induces an oxidative base modification that could result in transcriptional mutagenesis (Bregeon et al., 2009) or in DNA single-strand breaks (SSBs) (Lindahl, 1993), two processes that leads to genomic instability and cell death (Rodier et al., 2009)

Ann Rev Biochem 52:711760, 1983

Sung JY, Hong JH, Kang HS, Choi I, Lim SD, Lee JK, Seok JH, Lee JH, Hur GM: Methotrexate suppresses the interleukin-6 induced generation of reactive oxygen species in the synoviocytes of rheumatoid arthritis

J Rhuematol 20:18451849 Kamalakkannan N, Prince PSM (2006) Rutin improves the antioxidant status in streptozotocin-induced diabetic rat tissues

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