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Moreover, ceramide, a known toxic lipid released by the adipocyte, was recently found to be exported out of the adipocyte through exosomes to promote inflammation in macrophages

In other words, TEER is the reflection of the resistance that the epithelium is exerting against ions to cross from the luminal to the basolateral side

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Our results do not provide evidence that pain in the cLBP group was discogenic, but rather that biochemical disc degeneration was more severe in cLBP patients than controls, and that the difference depended on age and spinal level