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Extensive site-directed mutagenesis, ligand binding analysis, determination of pHrate profiles, and solvent deuterium isotope effects established the reaction mechanism for Arabidopsis GS and for the eukaryotic homologs (Herrera et al., 2007)

About 7%-12% percent of North American, European, and Australian people have this mutation

Such enzymes include the glutathione peroxidase family, the glutaredoxin family, the peroxiredoxin family, and others

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Whey protein concentrate has been shown to represent an effective and safe cysteine donor for GSH replenishment during GSH depletion in immune deficiency states