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In a previous study, we demonstrated that the bi-paratopic ELN22-108 is superior to Adalimumab in controlling sTNF--driven polyarthritis in Tg197 transgenic mouse model of polyarthritis, while in another study, we showed evidence that VNARs targeting an unrelated antigen are amenable to binding unique epitopes that consequently resulted in previously undocumented mechanism(s) of antigen neutralization 24,31

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Superoxide dismutase also showed a significant decrease (almost 35%) in enzyme activity in the liver and kidney of GK rats, which recovered moderately (20%25%) after exercise (Figure 2D)

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