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Specifically, they noticed a substantial decrease in the expression of lipogenic genes, including ACC , PPAR , and CPT-1a , following the administration of sodium butyrate therapy in comparison to the control treatment

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PPA exposure produced pronounced oxidative stress and disruptions in lipid metabolism, whereas post-treatment with omega-3 or vitamin B12, administered individually or together, partially normalized antioxidant defenses, modulated inflammatory enzyme activity, and altered microbial profiles

Increased expression of (immuno) proteasome subunits during epileptogenesis is attenuated by inhibition of the mammalian target of rapamycin pathway

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doi: 10.1093/humupd/dmz049 21 FattoriVZaninelliTHRasquel-OliveiraFSHeintzOKJainASunLet al