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ROS production and associated inflammation are closely related to aging and numerous chronic diseases as diabetes, cardiovascular atherosclerosis-related diseases (144, 145) and respiratory diseases, known risk factors for developing severe illness and death in patients with SARS-CoV-2 and COVID-19 disease

The generated GSSG was then reduced to GSH with the consumption of NADPH by GR

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NAC treatment increased extracellular total antioxidant power and total thiol molecules and enhanced intracellular GSH and patients outcome (106)

doi: 10.1007/s11356-015-5351-4 114 RizwanM.MeunierJ.MicheH.KellerC

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