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Apart from local inflammation, activation of glial cells (satellite glial cells, Schwann cells and immune cells) in the DRGs are also involved in the augmented inflammatory responses and enhanced neuronal excitability resulting in the development of pain hypersensitivity after chemotherapy treatment (Fumagalli et al., 2020)

Lorsque l'quilibre est rompu et que la concentration en glutamate atteint un niveau excessif dans la fente synaptique, ou encore lorsqu'il demeure trop longtemps dans cette fente synaptique, il peut hyperstimuler les neurones et provoquer leur mort

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While movement is essential for managing symptoms, certain activities can unfortunately do more harm than good

doi:10.1289/ehp.97105s4907

As with any medication, it's essential to follow the prescribed dosage instructions to ensure its effectiveness and minimize potential side effects