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Sallai guggul gum resin is known to be specific, non-redox, and non-competitive inhibitors of 5-LOX, a crucial enzyme of leukotriene biosynthesis

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Most rodent studies used: 10 micrograms/kg 100 micrograms/kg Administration routes varied by study: Intraperitoneal injection Subcutaneous injection Oral administration in drinking water Example reference: Sikiric et al., 2018 These dosages reflect controlled laboratory conditions and are not generalised outside experimental models

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doi: 10.1016/j.pscychresns.2017