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These behavioral abnormalities are exacerbated by social isolation and associated with deficits of social memory, spatial working memory and prepulse inhibition ( Animal models of poor motivation of SCZ are represented by the DA deficient mice induced, for example, with local neurotoxic injection with 6-OHDA in nucleus accumbens, mutant rodents with an overexpression of DA D2R (DR2-OE) or an overexpression of DA D3R (DR3-OE)

murinus or Lactobacillus reuteri , suggesting the influence of these bacteria on blood pressure regulation (Wilck et al., 2017)

97,98,99 HFpEF constitutes approximately half of all heart failure cases, particularly in T2D, and is defined by a left ventricular ejection fraction 50% with predominant exercise intolerance

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But inside the body, its role is much more interesting