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National Library of Medicine

The pathophysiologic mechanism of hyperpigmentation involves increased melanin synthesis and the inadequate transfer of the pigment from the melanocytes to the nearby keratinocytes

Evan with a varied diet, this group often do not get enough absorbable B12 from their food and often have a B12 deficiency

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The more useful question is not always, What can I add to this medication? It may be, What parts of my treatment plan are still missing? Those missing pieces may include: Adequate protein Resistance training Sleep improvement Hydration Constipation management Stress reduction Medication adjustments Treatment of an underlying metabolic condition Adding another peptide does not automatically solve these problems

The tradeoff remains the same: less volume, less precision