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However, when the cell detects an apoptotic stimulus, such as DNA damage or metabolic stress, the intrinsic apoptotic pathway is triggered and mitochondrial cytochrome c is released into the cytosol (Kroemer et al., 2007)

The Kyoto Encyclopedia of Genes and Genomes (KEGG) database is a powerful tool for analyzing in vivo metabolic networks

While it is by no means a substitute for sunscreen, it is a relevant complement within a comprehensive photoprotection strategy

TUNEL-positive signals that mark DNA fragmentation are often detected in testes with the loss of germ cells [31, 32]

Furthermore, gut microbiota is involved in the maintaining of the integrity of the intestinal epithelial barrier, in the protection against exogenous pathogens, in the maturation of the host gut immune system, and in the metabolism of xenobiotics [8]

Biology of Reproduction