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Tirzepatide, being approved, additionally carries a labeled boxed warning for thyroid C-cell tumors based on rodent studies

Vajro, P., Paolella, G

The carbohydrate-response element-binding protein is a target gene of LXR

Chondrocytes are cells believed to be found within cartilage tissue, and they possibly play a role in producing and maintaining the extracellular matrix, which consists of components like collagen and proteoglycans