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Folate and one-carbon metabolism nutrients from supplements and diet in relation to breast cancer risk

205 Following carboplatin treatment, ACSL1/FSP1 activation inhibits ferroptosis and reduces the sensitivity of cancer cells to platinum chemotherapy, promoting cell survival and metastasis

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For instance, elevated lactate concentrations upon ICU admission are independently linked to higher mortality in ischemic stroke, reflecting its dual role as both a metabolic substrate and a prognostic biomarker of disease severity [188]