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Description

PLoS Med 2009;6:e1000097 Murray J, Farrington DP, Eisner MP

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Since B12 is either present in animal tissues or produced by bacteria, there is no fruit or vegetable source of vitamin B12

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Hampton MB, Orrenius S

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These findings seem to parallel the inhibitory effects of bilirubin on superoxide production32 and on overall mitochondrial metabolism.33 In fact, pyrrole groups of bilirubin, present also in our compounds, have been suggested to compete with NADH on the active sites of mitochondrial dehydrogenases indicating possible mechanisms of these effects.33 This conclusion is also in accord with a report by Boloor, et al., who described marked protective effects of chlorophyllin on mitochondria-induced lipid peroxidation.34 It seems that observed anti-carcinogenic effects are mediated, at least partially, by direct inhibition of mitochondrial ROS generation

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In particular, levels of L-arginine, L-proline, and L-glutamic acid were elevated, whereas glutathione, L-tyrosine, and L-phenylalanyl-L-proline levels were reduced

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27 A few botanical therapies are: Systane (Alcon)

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