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Description

Following oral administration, Dolutegravir is rapidly absorbed with a high oral bioavailability when administered as a solution to fasted male rats and a single monkey (75.6 and 87.0%, respectively)

Molecules 28, 7142

Data availability All relevant data are within the paper and its Supplementary Information files

THE REPUBLIC OF UGANDA Ministry of Agriculture, Animal Industry and Fisheries An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author

doi: 10.3389/fmed.2021.620990 67 OffringaAKBourgonjeARSchrierMSDethRCvan GoorH

5-alpha reductase inhibitors (5-ARIs) impair AR signaling by blocking the conversion of testosterone to dihydrotestosterone (DHT), often used as an androgen deprivation (AD) therapy to induce prostate cell apoptosis, thus treating BPH