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( A ) HCT116 and SW480 cells were treated with RSL3 (1 and 5 M) or DMF (25 and 100 M) alone or in combination with FG4592 (100 M) with or without ferroptotic inhibitors Fer-1 (0.5 M) or Lip-1 (1 M) for 24 hours, and cell death was assayed

J Clin Investig 102:19942001

& Vctor, V

U2OS cells lacking GOLPH3/3 L also had reduced colocalization of induced LYSET-10xGCN4 with GM130 (Fig

Histone deacetylasemediated silencing of AMWAP expression contributes to cisplatin nephrotoxicity