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HTCS is a cytoplasmic membrane-spanning protein that comprises all domains of a classical two-component system in one polypeptide (N-terminal extracellular sensor, cytoplasmic histidine kinase, and response regulator)

During an allergic reaction, immune cells generate oxidative stress as part of the inflammatory response, contributing to tissue damage and prolonged symptoms

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Neuroendocrinol Lett (2009) 30(6):67793