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Blood loss associated with repeated blood sampling or surgery Nutritional deficiencies Potential oxidant injury, resulting in premature clearance of newly formed RBCs (called neocytolysis) (Astin and Puthutcheary 2014)

Reduces Chronic Inflammation Inflammation is a natural immune response to injury or infection, but chronic inflammation can harm the body and weaken immunity

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Cytochrome P450 polymorphisms are associated with reduced warfarin dose