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Ketogenic and low-sugar diets for patients with cancer: perceptions and practices of medical oncologists in Canada

Cisplatin exerts a strong promoting effective via accumulation, therefore, it tends to induce nephrotoxicity and often causes renal cell damage [170]

Beyond its redox coenzyme activity, NAD + serves as a substrate for sirtuins, poly(ADP-ribose) polymerases (PARPs), and other signaling enzymes that consume NAD + during the processes of DNA repair, deacetylation, and cellular stress response

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