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doi: 10.1016/j.tcb.2020.09.006 72 LiuCZhouYGuoDHuangYJiXLiQet al

Typically, this occurs when the virus reactivates during oral herpes recurrences and enters the central nervous system

[DOI] [PubMed] [Google Scholar] 9.Acilmis YG, Dikensoy E, Kutlar AI, Balat O, Cebesoy FB, Ozturk E, Cicek H, Pence S

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The CDC criteria require disabling fatigue lasting more than 6 months that cannot be explained by exclusionary medical or psychiatric diagnoses) 8,9,10 plus at least 4 of 8 ancillary symptoms: short term memory of concentration problems, sore throat, sore lymph nodes, myalgia, arthralgia, headache, sleep disturbance, and post-exertional malaise (exertional exhaustion)

In this context, the exploration of ME/CFS pathogenesis has increasingly focused on the microbiome-gut-brain axis, revealing a complex interplay between intestinal dysbiosis and the multifaceted symptomatology of this debilitating condition [10]