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On the 15th day, the mice were fasted for 12 h and anesthetized with pentobarbital sodium

The GSH/GSSG ratio usually indicates the level of cellular oxidative stress, which accelerates the conversion of GSH to GSSG and decreases the GSH/GSSG ratio [26]

The S4 transmembrane segment of the channels is rich in positively charged basic residues, and S4 is agreed to be important in voltage sensing, although the conceptual and structural basis for gating charge movement is the subject of intense controversy

the thiol is the thiol of a cysteine residue

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