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Therefore, we suggest that further investigations for assessing their potential as therapeutic agents against COVID will be essential

Cancer Cell 7 , 101111 (2005)

Control of cell cycle and immortality HDAC2 The role of histone deacetylase 2 (HDAC2) in GBM appears to regulate acetylation of histones 3 and 4 which were in turn found to potentiate brain tumor stem cell (BTSC) self-renewal

Specifically, mtDNA mutations lead to mitochondrial dysfunction, disrupting OXPHOS, reducing ATP production, and increasing ROS generation, which ultimately trigger apoptosis and genomic damage [97]

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Kilian J, Whitehead D, Horak J et al (2010) The AtGen Express global stress expression data set: Protocols, evaluation and model data analysis of UV-B light, drought and cold stress responses