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The therapeutic index based upon animal studies is small

Lin B, Lu L, Wang Y, et al

Alcohol Res Health: J Natl Inst Alcohol Abuse Alcohol 27:277284 Garca-Baos A, Alegre-Zurano L, Cantacorps L et al (2021) Role of cannabinoids in alcohol-induced neuroinflammation

Full text: Knezevic, J., Starchl, C., Tmava Berisha, A., & Amrein, K

At a pH of 7.4, primary nucleation proceeds spontaneously and is the fastest in the absence of other governing factors (Dada et al., 2023) whereas the critical concentration of -synuclein needed to undergo LLPS is the least at pH 5.5 probably owing to the proximity of the isoelectric point of -synuclein near that pH assisting separation of proteins from the solution (Hou et al., 2023)

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