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There is a possibility of misdiagnosis due to overlapping symptoms of the different disorders

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This colorimetric approach relies on the reaction between 5,5-dithio-bis(2-nitrobenzoic acid) (DTNB) and the sulfhydryl group of GSH

Lactulose to mannitol ratio in humans The ratio of urinary excretion of lactulose to mannitol (LA/MA) was used to measure the intestinal mucosal permeability in ten RA patients and ten healthy controls who underwent colonoscopy, with higher ratios indicative of increased intestinal permeability as previously described 33

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