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or an N-oxide, crystalline form, hydrate, or pharmaceutically acceptable salt thereof, with the proviso that: when R 3 is ethyl, R 1 and R 2 cannot be both H, O, or when R 3 is ethyl and at least one of R 1 or R 2 is H, R 1 or R 2 cannot be As used herein, ferroptosis means regulated cell death that is iron-dependent

Acta Derm Venereol 89(3):314315

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Specifically, autophagy-mediated histone deacetylase inhibition promotes acetylation of HMGB1, leading to its release during ferroptosis [100]

doi: 10.1172/JCI29881 34 DavisJEGablerNKWalker-DanielsJSpurlockME

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