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The enzyme does not require metal ions for its activity

In 2003, Agre shared the Nobel Prize in Chemistry for discovering aquaporins, a family of water channel proteins found throughout nature and is responsible for numerous physiological processes in humans and is implicated in multiple clinical disorders

Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism

Research indicates that elevated fibromodulin expression in diabetic patients may increase the level of intracellular iron and oxidative stress by promoting the internalization and degradation of iron transporters in intestinal cells and monocytes [67]

Sharkey Jean E

Since inhibiting T cells can decrease both humoral and cellular immunity, the induced immunosuppressive agents targeting T cells are being recognized as currently the most effective medicine ( Table 1 )