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A major concern is the association with an increased incidence of autoimmune inflammation and related disorders, attributable to the ability of certain probiotic strains to overactivate immune responses

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in Biochim Biophys Acta (1984) Vol.766 pp161-8 Intra-vesicular pH-changes in cytochrome c oxidase vesicles as a result of ferrocytochrome c oxidation Thelen, M