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Conversely, decreased Cav-1 level or obstructed Cav-1 and eNOS interaction can release eNOS favoring its activation and induction of nitric oxide production that is known for its protective effect on vessels 44,45

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Additionally, Nrf2 knockout lead to the formation of fibrotic tissues, indicating that Nrf2 is a potential ferroptosis-related therapeutic target and biomarker for evaluating the severity of PF [215]

Dormancy Period: Rickettsial pox is generally mild and resolves within 23 weeks if untreated

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