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Most commonly it is found in individuals with small intestinal bacterial overgrowth and a highly acidic diet that is low in alkaline buffering minerals (12)

As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels

Every drop counts, and so does your well-being

10.1038/ncprheum0531 Nat Clin Pract Rheumatol

Ongoing studies, including VA-IMPACT (NCT02915198) for secondary prevention in patients with prediabetes and atherosclerotic cardiovascular disease and emerging trials in atrial fibrillation (e.g., NCT05878535), will be critical

doi: 10.1016/j.jep.2024.117912