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Accounting for over 80% of all strokes, its pathological process involves abnormal ion gradients, glutamate excitotoxicity, excessive reactive oxygen species production, and mitochondrial dysfunction

The disease is primarily characterized by motor symptoms such as bradykinesia, postural instability, rigidity, and tremor, as well as non-motor symptoms

doi: 10.1016/0885-5765(90)90010-U 29 GuimaresR

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New insights in cannabinoid receptor structure and signaling

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