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Clinical Results High-dose reduced glutathione has shown effectiveness in protecting against kidney and urinary tract toxicity caused by certain chemotherapies

The GST domain is also found in S-crystallins from squid, and proteins with no known GST activity, such as eukaryotic elongation factors 1-gamma and the HSP26 family of stress-related proteins, which include auxin-regulated proteins in plants and stringent starvation proteins in Escherichia coli

PTMs such as phosphorylation and acetylation are labile and sub-stoichiometric, thus requiring additional sample processing considerations (e.g., phosphatase inhibitors) to avoid artifacts and enrich low-abundance PTMs

These results suggest AC as a potential therapeutic candidate for toxic inhalation-induced lung damage

L.LiuD.WyttenbachT.BowersM