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doi: 10.3389/fimmu.2012.00288 219 MaesMCouckeFLeunisJC

injections of 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages), 300 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) in comparison with vehicle-treated age-matched chow-fed C57BL/6 J mice ( n = 16 mice and n = 8-11 cages) for 14 days

The European Medicine Agency (EMA) has recently approved ubiquinolthe reduced form of CoQ 10 (CoQ 10 H 2 )as an orphan drug for the treatment of primary CoQ 10 deficiency ( However, patients suffering from secondary CoQ 10 deficiency may fail to respond to CoQ 10 supplementation (Pineda et al., 2010)

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However, OPT2 failed to complement the seo1 to any significant extent (Fig 6a)