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Sulfasalazine Alters Intracellular Metabolites and Increases ROS in A549 Cells Induction of Ferroptosis by Erastin Erastin is a known inducer of ferroptosis

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In a study using a cisplatin-resistant GC xenograft model, the combination of Erastin and cisplatin significantly enhanced tumor suppression and improved immune cell infiltration profiles, suggesting its potential to modulate the immunological microenvironment in GC (114)