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Role of insulinlike growth factor binding proteins in controlling IGF actions

However, the full spectrum of probable adverse unfavorable effects remains unclear

For intravenous (IV) administration, the dosage may be higher, typically between 10-20 mg/kg of body weight

In general, phenolic and flavonoid components present in the extract may provide strong antioxidant property to plant by acting as ROS scavengers, hydrogen donors, reducing agents, singlet oxygen quenchers and metal chelators, [86]

Through proteomic analysis, we previously reported an upregulation of proteins involved in both beta-oxidation and the tricarboxylic acid cycle in patient-derived fibroblasts, with the possible purpose of increasing oxidative phosphorylation and, consequently, mitochondrial ATP production 26

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