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One-way analysis of variance (ANOVA) test was used to determine difference among more than two groups

However, these researches ignore the effect on surrounding normal tissues, as these compounds lack specific targeting to tumor cells

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4 The resulting energy deficit and accumulation of damaged mitochondria contribute to neuronal degeneration and loss of nerve fibers

The main target for Grx2 in mitochondria is Complex I, although UCP3 and the 2-oxoglutarate dehydrogenase (OGDH) have been also shown to be deglutathionylated by Grx2

CD is characterized by deeper, transmural inflammation that often requires more aggressive treatments such as corticosteroid therapies