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Besides, this condition decreases the activity of cellular gluthatione peroxidase, an intracellular antioxidant enzyme that reduces hydrogen peroxide to water with the prevalence of GSSH on GSH

To understand ARA-290, we have to look at a hormone you might already know: Erythropoietin, or EPO

The strains predicted to produce these vitamins belong to dominant gut microbiota genera such as Bacteroides , Prevotella , Clostridium, Faecalibacterium and Fusobacterium , and less dominant but prevalent gut taxa such as lactobacilli from the Limosilactobacillus reuteri, Limosilactobacillus fermentum and Lactiplantibacillus plantarum species

10.1038/nrg.2016.150 Nat

Functionally all of these phenotypes are characterised by loss of several homoeostatic molecules, which decreases neuronal support and neuroprotection ultimately resulting in neuronal death