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Developed by Metabolic Pharmaceuticals as a candidate anti-obesity agent

Isatuximab acts through fc-dependent, independent, and direct pathways to kill multiple myeloma cells

Published research on 5-Amino-1MQ originated with NNMT-inhibitor screens reported in the mid-2010s

Note on the tolerance/diminishing-effect claim: the widely repeated effect fades after 4 to 6 weeks figure appears as repeated online claims, not in any primary study I could locate