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The peptide downregulates or inhibits key lipogenic enzymes including fatty acid synthase and acetyl-CoA carboxylase, which are responsible for converting excess dietary carbohydrates and other substrates into fatty acids for storage

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Brain, Behavior, and Immunity 87:715724 Dehhaghi M, Heng B, Guillemin GJ (2023) The kynurenine pathway in traumatic brain injuries and concussion

doi: 10.3389/fcimb.2025.1488264 Received 29 August 2024 Accepted 24 February 2025 Published 11 March 2025 Volume 15 - 2025 Edited by Xiangtian Yu, Shanghai Jiao Tong University, China Reviewed by Zeneng Wang, Cleveland Clinic, United States Lin Chen, Northwest University, China Updates Copyright 2025 Su, Wu, Wang, Xie, Xiao, Su, Tang and Yao

ICP6 prevents RIP1 activation to hinder necroptosis signaling

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