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As the pathologic progress continues, the neurodegeneration of formerly impaired regions is also aggravated (Braak et al., 2020)

Palasuwan A, Kittisakulrat T, Amornrit W, Soogarun S, Wiwanitkit V, Pradniwat P

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Further, there is a lack of direct evidence between ferroptosis and the most widely used anti-rheumatic drugs in the treatment of RA patients, which requires further investigation