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Diabetologia 59, 10981103

Figure 8A )

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Theoretically, masculinization of the brain occurs under the influence of testosterone, during the prenatal and/or neonatal period and together with the activation of a testosterone-mediated puberty, a male gender identity develops, overriding the female sex of rearing

The results of the regression indicated the two predictors explained 31% of the variance ( R 2 = 0.0.31, F (2, 24) = 4.86, p = 0.018)

This microbial LPS can directly translocate to the brain, where it activates microglia through the TLR4/NF-B pathway, promoting type I interferon signaling while suppressing type II interferon-driven autoimmune responses, thereby influencing susceptibility to autoimmune diseases such as experimental autoimmune encephalomyelitis (EAE) [1, 287]