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The STEP 4 withdrawal trial demonstrated that continued Semaglutide therapy was needed to maintain weight loss, as patients switched to placebo regained weight over 48 weeks (Rubino et al., JAMA 2021

doi: 10.1097/FJC.0000000000001148 83 SunWXGaoYYCaoYLuJFLvGHXuHQ

doi:10.1016/j.nut.2021.111231 Park S, Kang S

It can also promote macrophage-mediated ADCP

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